The RoadMap to Improve Drug Discovery

3D In Vitro Models

The technological advancement and the consequent emerging of 3D models offer more opportunities for pre-clinical therapies screening, in a way to envision precision and personalized medicine approaches.

Cellularis is working on the development of new bioengineering strategies for the construction of models to mimic several aspects of the tumor microenvironment components and dynamics.

Precision bioengineered in vitro 3D models recapitulate the hallmarks of human disease and impact therapies discovery pipeline

DESIGN PHASE

BIOENGINEERING PHASE

VALIDATION PHASE

Lung Tumor

Physiomimetic 3D model comprising tumor-stroma lung-specific decellularized matrix

Pancreatic Tumor

Physiomimetic 3D model comprising tumor-stroma pancreatic-specific decellularized matrix

Breast Tumor

Physiomimetic 3D model comprising tumor-stroma breast-specific decellularized matrix

Prostate Tumor

Physiomimetic 3D model comprising tumor-stroma prostate-specific decellularized matrix

Glioblastoma

Physiomimetic 3D model comprising tumor-stroma glioblastoma-specific decellularized matrix