Funded Projects

New Prime Editing and non-viral delivery strategies for Gene Therapy

The EdiGenT project introduces a non-viral nanoparticle-based system with minimal side effects for the delivery of gene editing components in cells. 

Developing novel inhaled bioengineered Extracellular Vesicle RNA based advanced therapeutics, delivered by tailored aerosol delivery technology for the treatment of lung cancer

INSPIRE will employ an aerosol-based approach to efficiently deliver genetically modified EVs from mesenchymal stromal cells through the mucus barrier, as a therapy against lung cancer. Cellularis will bioengineer innovative patient-derived ECM-tumor-stroma organoid models that recapitulate ECM aberrant crosslinking.

Integrated nano-photonic OMICs bio-SENSor for lung cancer

The European project OMICSENS aims to develop a radically new integrated nano-photonic omics biosensing platform for the early and accurate detection of therapy resistance in lung cancer, improving patient prognosis and enabling future applications in personalized cancer medicine.

Cost-effective immunotherapy platforms target bacterial infectious diseases

The NanoBiCar project aims to revolutionise the treatment of bacterial infections by developing an innovative mRNA-based immunotherapy using lipid nanoparticles to effectively eliminate both intra- and extracellular bacteria, with tuberculosis as a proof of concept, including drug-resistant forms.

Nature-Inspired Prophylactic Lubricants Against HIV-1 and HSV-2

The NatProLub project proposes to develop prophylactic lubricants with antiviral properties inspired by nature. The key objective is to address the gender imbalance in sexual health and improve prophylaxis against contraction of HIV.

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